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Myelodysplastic Syndromes - Oren Zarif - Myelodysplastic Syndromes


The World Health Organization classifies myelodysplastic syndromes into subtypes based on the blood cell type they affect. The most common subtype is associated with a lower-than-normal number of red blood cells. It also causes anemia. The underlying cause of myelodysplastic syndromes is unknown. If you notice any of these symptoms, contact your doctor for further testing.

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Treatment for myelodysplastic syndromes depends on the severity and type of disease. Treatments range from blood transfusions to growth factors to help stimulate bone marrow. A bone marrow transplant may also be an option. Treatment for the disorder may include chemotherapy, radiation therapy, and stem cell transplants. However, there is no cure for myelodysplastic syndromes. Therefore, patients with this disease should seek medical attention as soon as possible.

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A person with this disease is at risk of contracting infections and bleeding frequently. The condition is caused by a lowered number of white blood cells in the blood. The disease can be triggered by heavy exposure to chemicals, such as benzene, which is found in gasoline and cigarette smoke. Treatment-related MDS is more difficult to treat than de novo MDS. Approximately 90% of people with MDS have de novo MDS. A small minority have bone marrow damage as a result of chemotherapy or radiation therapy.

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Those with the disorder have a low number of blood cells of a particular type, called cytopenia. These cells are abnormal in their composition and function, making the patient prone to infection, frequent bleeding, and anemia. In some cases, people with myelodysplastic syndromes may even develop cancer of their bone marrow or blood cells. A good diagnosis is based on symptoms, not age.

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Treatment for Myelodysplastic syndromes begins with a blood test. A blood test will identify the specific type of disease you have. Occasionally, your doctor may recommend a bone marrow transplant, also called a stem cell transplant. This procedure will replace damaged bone marrow with healthy bone marrow from another donor. It is also recommended to take regular blood tests to monitor symptoms.

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While the underlying cause of myelodysplastic syndromes is unknown, the condition may progress into leukemia in some cases. If the condition is left untreated, it can lead to acute myeloid leukemia. Symptoms of the condition include a gradual fall-off in the amount of blood cells and worsening anemia. Some people may even experience bleeding or an infection. Antibiotics may be prescribed in some cases.

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If you've been diagnosed with MDS, your health care team will work to relieve your symptoms and manage the emotional impact of the illness. Depending on your stage of the disease, treatment options can delay or even reverse the progression of your condition. While medical care will include chemotherapy or other types of treatment, lifestyle changes can also help. An active lifestyle and healthy diet can help you manage your symptoms. Often, symptoms are more obvious when symptoms occur after a diagnosis.

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Some of the symptoms of MDS include fatigue, anemia, and thrombocytopenia. The absence of sufficient red blood cells in the body can make people pale and irritable. Patients with MDS may also experience chest pain, palpitations, or even pale skin. In addition, low platelet counts can lead to a higher risk of developing bacterial or fungal infections. In addition to bleeding, patients with low platelet levels can experience excessive bruising and spontaneous bleeding. Some may even suffer from sinus infections and nasal congestion.

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In addition to the physical manifestations, MDS is sub-classified based on the type of blast cells found in the bone marrow. The World Health Organization (WHO) has identified six subtypes of MDS, and each has different symptoms and treatment options. If you are experiencing any of these symptoms, contact your doctor as soon as possible for further testing and treatment. You can also undergo radiation therapy and chemotherapy to treat your symptoms.

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While the specific symptoms of MDS vary from person to person, it is important to note that they are all common and can range from mild to severe. The exact symptoms of the disease depend on the type of blood cells affected and the stage of the disease. While a mild case may be associated with no symptoms, it is still important to seek medical attention as early as possible, as a diagnosis can only come after extensive testing.

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