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Primary Central Nervous System Lymphoma Symptoms- Oren Zarif - Primary Central Nervous System


While most patients have no symptoms at the time of diagnosis, doctors may recommend undergoing certain tests to identify signs of Primary Central Nervous System Lymphoma. These tests will determine whether the disease has spread or recurred. Your doctor may also want to order blood tests to see if you have low levels of white blood cells and platelets, which are vital for fighting infection. If these tests are negative, your doctor will recommend treatment.

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Although establishing a definitive diagnosis of primary CNS lymphoma is difficult, familiarity with the disease can greatly improve your suspicion. Emergency room and outpatient clinic physicians, for example, should have an adequate level of suspicion. Using steroids to treat the patients is a common way to decrease cerebral edema, but they decrease the diagnostic yield. The risk of infection with steroids is low.

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Other primary CNS lymphoma symptoms include a throbbing headache, changes in personality, vision, speech, and bowel movements. The patient may also experience numbness or tingling in limbs, a reduced sex drive, and a change in personality. Patients may also experience nausea or vomiting. Patients may also experience unexplained weight loss.

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A CT scan is recommended when a diagnosis of primary CNS lymphoma is suspected. The lesions of PCNSL are usually bulky, contiguous with the ventricular or meningeal surface. In contrast to meningiomas, they are hyperintense on T1 and hypointense on T2. In addition, CT scans typically show diffusely enhancing masses. Occasionally, ring-like enhancement occurs, although this is rare.

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If you or someone you know is suffering from primary CNS lymphoma, you should schedule an appointment as soon as possible. Symptoms may vary, and doctors may recommend treatment based on your specific case. There are many different types of primary CNS lymphoma, including DLBCL and FML. For more information, download our free Primary Central Nervous System Lymphoma Fact Sheet.

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Those with immune system disorders, such as HIV, have a higher risk of getting this type of cancer. While it is rare, people with weakened immune systems are at increased risk. Those with HIV positive status and organ transplants are also at an increased risk. Overall, there are nearly 1,500 new cases of primary CNS lymphoma in the United States each year. So, how can you recognize your symptoms?

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Other symptoms of Primary CNS lymphoma include headaches, nausea, floaters, and increased intracranial pressure. Some people with this type of cancer may experience seizures or even gait imbalance. Neurological symptoms may also include vomiting and nausea. Patients with primary CNS lymphoma may also experience fever and night sweats. In addition to a range of neurologic symptoms, patients with this type of cancer may also experience weight loss.

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Although primary CNS lymphoma does not spread through the body's lymphatic system, it can affect any part of the central nervous system. It affects the eye, the spinal cord, and the brain. Primary CNS lymphoma develops when the body produces abnormal lymphocytes, which are white blood cells that normally fight infection. These abnormal lymphocytes are usually B-cell lymphocytes. Diffuse large B-cell lymphoma is a fast-growing non-Hodgkin lymphoma.

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Although the survival time of patients with primary CNS lymphoma is remarkably long, the median duration of disease-free survival is only about 44 months. It is unclear which treatment options are best for this type of cancer. Researchers have concluded that standard chemotherapy regimens are ineffective. The difficulty of penetrating the blood-brain barrier likely has something to do with this, but the median survival is currently 44 months.

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The symptoms of Primary CNS lymphoma are different from other types of cancers. Unlike Hodgkin lymphoma, which spreads throughout the body, primary CNS lymphoma begins in the central nervous system. It can develop in the eye and spread throughout the rest of the body over time. Because it begins in the CNS, it is sometimes called ocular lymphoma.

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The treatment for primary central nervous system lymphoma consists of high-dose chemotherapy. A patient may receive an autologous stem cell transplant in order to control the disease for as long as possible. The chemotherapy process is extremely intensive, and may also include radiotherapy to the brain and spinal cord. You should schedule periodic appointments with your healthcare provider, and be sure to discuss your symptoms and concerns with him or her.

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The symptoms of Primary CNS lymphoma depend on the type of PCNSL. Large B-cell lymphoma is the most common type, accounting for nearly 90 percent of all cases. T-cell PCNSL, on the other hand, is much rarer and is characterized by less widespread involvement of the CNS. The main symptoms of PCNSL are ocular and leptomeningeal involvement, decreased ocular lymphoma, and a decreased incidence of intracranial involvement.

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