Adrenocortical carcinoma is a rare disease. Only about 25 new cases are diagnosed each year in children in the United States. The incidence is about 15 times higher in southern Brazil. Men and women are equally at risk. Among men, the incidence is significantly higher than that of women. The tumors are often found in the adrenal glands and in the pituitary gland.
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Although the tumors are rare, many patients have a history of Cushing syndrome. Symptoms of Cushing syndrome include round or double chin, generalized obesity, growth failure, and hypertension. Many cancers are unrelated to a known cause, but may result from a combination of genetic and environmental factors. Some cancers are inherited, including neurofibromatosis, lupus, tuberous sclerosis, and ataxia-telangiectasia.
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In addition to symptoms, a patient may have additional signs of Cushing syndrome. These include round face, double chin, generalized obesity, and hypertension. Despite the fact that many cases of adrenocortical cancer are asymptomatic, it is important to seek medical attention as soon as possible. To learn more about this condition, read about the treatment options for patients.
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Some people with a family history of the disease may have signs of Cushing syndrome, including a round face, double chin, and generalized obesity. The signs of Adrenocortical Carcinom-A can vary greatly. If you have one or more of these risk factors, it's important to see your doctor. You can find out more about this condition by reading the risk factors below.
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Several symptoms may be present in a person with adrenocortical carcinoma. If you're suffering from any of the above symptoms, you should visit a doctor as soon as possible to get a diagnosis. Your doctor will give you an accurate diagnosis and the best treatment options available for your specific case. They will make sure to examine you and perform a complete and thorough examination.
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Physical exam is essential. Your doctor will check for signs of adrenocortical tumors. During the physical exam, the physician will ask you about your lifestyle and previous illnesses. A urine test will measure 17-ketosteroids and cortisol levels in the blood and may indicate adrenocortical cancer. A normal blood glucose level will not reveal the presence of an adrenocortical tumor.
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In addition to cancer-causing cells, adrenocortical carcinoma can also be found in other parts of the body. It can be locally limited to the adrenal gland, or it can spread to nearby lymph nodes and organs. Some cases of adrenocortical carcinoma may also spread to other parts of the body. Adenomas can be found in the lung, bone, and peritoneum.
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The most common symptoms of an adrenocortical cancer are pain, unexplained fatigue, and loss of appetite. Some patients may show signs of other conditions in addition to the adrenocortical cancer. Other symptoms are not easily diagnosed. During the initial stages of the cancer, there are no obvious signs of the disease. But, if the tumor spreads to other parts of the body, it can lead to complications, including kidneys and bones.
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Although the disease is rare, it can cause numerous other symptoms. Muscle weakness, a deepened voice, and weight gain are all symptoms of adrenocortical cancer. Some patients may not experience any symptoms. Other signs of an adrenocortical tumor may include growth of fine hair and a lump of fat. In addition to these, the doctor may notice some of the following symptoms in a patient.
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In 60% of patients, the symptoms of an adrenocortical cancer are caused by excessive secretion of hormones. Biochemical hormone tests can reveal the existence of the tumors and their functioning. In the remaining patients, the cancer is diagnosed due to the presence of adrenocortical carcinoma symptoms. The first step in diagnosing an adrenocortical tumor is to perform an ultrasound. The ultrasound will detect the abnormality in the adrenal gland.
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Although adrenocortical cancer is rare and has no known cause, it is associated with certain genetic syndromes. A tumor with an abnormal p53 gene can cause the development of an adrenocortical cancer. In addition, adrenocortical cancer symptoms can include abdominal pain. A doctor can perform imaging tests to look for the tumor. Blood tests can also check for hormone levels.
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