In 60% of the cases, patients seek medical attention because of symptoms related to excessive hormone secretion. Imaging studies reveal that up to 80% of tumors are functioning. The second most common presenting symptom is unspecific abdominal pain. However, adrenocortical carcinoma is also diagnosed as a result of an unrelated medical condition. If the cancer is caught in its early stages, it may be curable if detected at the earliest.
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Although some patients have a genetic predisposition, the majority of patients show no signs at all. Most ACC cases occur during childhood. Peaks are usually around age five and forty. Males are more likely to develop a functioning ACC than females. Most adrenocortical cancers are inherited, but not all. Women are more likely than men to have a functioning adrenocortical gland.
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Some patients with adrenocortical cancer have the symptoms of Cushing syndrome, a disease caused by a hormone imbalance. These symptoms may include a double chin, round faces, generalized obesity, hypertension, or decreased libido. While the exact cause of adrenocortical cancer is unknown, some inherited conditions are linked to it. Some inherited conditions include neurofibromatosis, tuberous sclerosis, ataxia-telangiectasia, and tuberous sclerosis. Most patients with adrenocorticism will have no symptoms at all.
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There is currently no known cause for adrenocortical cancer. However, genetic syndromes are associated with an increased risk of developing the disease. This type of cancer is caused by an abnormality in the p53 gene. If caught in its early stages, adrenocortical carcinoma is highly curable, but most patients will develop adrenocortical cancer at a later stage.
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Other signs of adrenocortical cancer include a deepening of the voice, swollen breasts, and vaginal bleeding. In some cases, men with adrenocortical cancer may also experience sexual dysfunction. Some patients with the disease will exhibit male characteristics, such as masculine attributes. Other symptoms include a deepening of the voice.
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Some people with adrenocortical cancer may experience unexplained pain or swelling of their sex organs, irregular menstrual cycles, or vaginal bleeding. The presence of any of these symptoms is indicative of adrenocortical cancer. While adrenocortical cancer can be life-threatening, it is often diagnosed by accident.
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Those with adrenocortical cancer should see a doctor immediately if they experience any of these symptoms. It is important to note that some patients with adrenocortical carcinoma will have signs of Cushing syndrome. These include a double chin, generalized obesity, and hypertension. Other signs of adrenocortical cancer may include abdominal pain or a sensation of fullness.
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The most common symptoms of adrenocortical cancer include deepening of voice, swelling of breasts, and vaginal bleeding. Unlike men who produce too much testosterone, patients with adrenocortical cancer usually do not display any symptoms. Other symptoms include vaginal bleeding and irregular menstrual cycles. Some people with adrenocortical carcinoma may also have certain genetic conditions.
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Most patients with adrenocortical cancer have signs of Cushing syndrome. They are characterized by a double chin, generalized obesity, and high blood pressure. Approximately ten percent of patients with adrenocorticism have signs of the disease. Some people may have symptoms of both types. But adrenocortical tumors do not have any symptoms.
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A physical exam will show signs of the disease and any abnormalities. A medical history will help determine whether the cancer is asymptomatic or has spread to other parts of the body. The doctor may also do a blood test called a PET scan. This test uses a radioactive glucose to create a picture of the body's metabolism. A malignant tumor cell will show up brighter in a PET scan than a benign tumor.
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The symptoms of adrenocortical cancer are often not obvious and may be mistaken for other conditions. In women, adrenocortical cancer is a rare condition that affects a few percent of the population. If you suspect adenocortical tumors in your body, you should see your doctor immediately. During your exam, your physician will also check for any abnormalities that are present.
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