Some patients may have a hereditary predisposition to adrenocortical cancer, but the majority of cases are sporadic. The disease typically peaks in children younger than five and continues into adulthood, peaking around age 40 to 50. During childhood, the tumors tend to be smaller and less aggressive, but they can still be dangerous. While men are more likely to develop nonfunctioning ACCs, women are more likely to develop functioning ACCs.
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While men who have a family history of the disease are more likely to develop it, women who have a family history of this cancer are much more likely to be diagnosed. Other symptoms of the disease include vaginal bleeding, abnormalities in menstrual periods, and deepening of voice. However, in many cases, there are no symptoms. If you suspect adrenocortical cancer, consult with a doctor.
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Typical signs and symptoms of this type of cancer include deepening of voice, swelling of the breasts, and abnormal menstrual cycles. A few percent of patients also display signs of Cushing's syndrome, including a round face, double chin, and generalized obesity. While adrenocortical cancer usually has no specific cause, some tumors are caused by inherited conditions. Among these are neurofibromatosis, tuberous sclerosis, ataxia-telangiectasia, and Li-Fraumeni syndrome. Some cases are also associated with MEN1 or MEN2, a gene mutation that affects the function of the adrenocortical gland.
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The symptoms of adrenocortical cancer may be vague and hard to pinpoint. The tumor is nonfunctioning and may not cause any symptoms. If it grows larger and spreads to other parts of the body, the cancer can become very aggressive and even life-threatening. A five-year survival rate for people with this type of tumor is about 50 percent, and drops to thirty-five percent in those who cannot undergo surgery.
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Symptoms of adrenocortical cancer may include abdominal pain, an unusually deep voice, or a full abdomen. While these symptoms are not specific to adrenocortical cancer, they can occur in both men and women. A doctor will need to perform imaging tests to determine if adrenocortical cancer is present. If it does, the doctor will conduct an MRI.
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Symptoms of adrenocortical cancer can include unspecific abdominal pain, fatigue, and fever. Generally, the symptoms of an ACC are similar to those of adenomas, which are benign tumors. Those who have no symptoms are unlikely to have adrenocortical cancer. Adenomas are a common type of adrenocortical tumor and are nonfunctional. They do not spread and are not cancerous.
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Symptoms of adrenocortical cancer include abdominal pain, fullness, and a rounded face. In some cases, the tumors may not be apparent in early stages, but it is important to seek medical attention if it occurs. A lump of fat can also be indicative of adrenocortical carcinoma. When it becomes large enough, it will likely begin to grow in adrenocortical tissue and cause other complications.
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Other symptoms of adrenocortical cancer may include a deepening of the voice, a double chin, vaginal bleeding, and irregular menstrual periods. While these symptoms are common with adrenocortical cancer, they are not always specific to the disease. Some men with adrenocortical tumors do not have any symptoms, while others may have several.
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In most cases, symptoms of adrenocortical cancer include abnormal amounts of certain hormones. These abnormal levels can lead to serious complications, such as hyperaldosteronism, high blood pressure, and Cushing's syndrome. Additionally, some patients experience anorexia and gastrointestinal problems. A few may even develop metastases, which can spread to other parts of the body.
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If detected early, adrenocortical cancer may be curable. Once detected, the cancer cells can be eradicated and the patient can live a normal life. It is important to note that the symptoms of adrenocortical cancer vary greatly between individuals. Some people are more vulnerable to adrenocortical tumor than others, and there is a chance they may be hereditary.
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Although the exact cause of adrenocortical cancer is unknown, it is most often caused by a preexisting adenoma. If the tumor has spread, treatment may involve chemotherapy. Some people may also experience nausea and vomiting. If the symptoms persist, they may be signs of an adrenocortical cancer. While the diagnosis depends on the stage of the tumor, it is vital to understand the effects of the cancer.
