The diagnosis of adrenocortical carcinoma depends on several factors, including the size and speed of the tumor, changes in specific genes, and whether the tumor has spread to other organs. The prognosis is also influenced by the number of affected organs, and a proper treatment plan must be created before the cancer progresses. Patients suffering from this type of cancer should undergo radiation therapy.
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A physical examination may reveal signs of adrenocortical tumors. Urine tests may also reveal abnormal hormone levels. Imaging studies and blood tests may be performed to confirm the diagnosis. In some cases, ultrasound can also reveal an adrenal tumor. Often, symptoms will appear during the early stages of the disease, but early detection is essential. Some patients may experience no symptoms at all.
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Children with adrenocortical cancer may experience no symptoms for a decade after diagnosis. Some patients may show signs of Cushing syndrome, which include a round face, double chin, generalized obesity, hypertension, and growth failure. While the cause of adrenocortical cancer is unknown, it is often the result of a combination of inherited and environmental factors. ACC is more common in women than in men, and its incidence is five times greater in southern Brazil.
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Most adrenocortical tumors are benign and nonfunctioning. The cancers can be smaller than four centimeters in diameter and occur in only one adrenal gland. Sometimes, they can spread to neighboring organs, lymph nodes, or bones. Some adrenocortical tumor is associated with Li-Fraumeni syndrome, which causes a number of symptoms including sexual dysfunction.
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In addition to tumors in the adrenal gland, adrenocortical cancer can cause abnormalities of the gastrointestinal tract, lungs, and breasts. In some cases, the disease can cause an irregular menstrual period or even vaginal bleeding. Symptoms of adrenocortical cancer may be difficult to detect in the early stages. Nevertheless, a doctor may be able to diagnose the tumor and give the patient the necessary treatment.
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A diagnosis of adrenocortical cancer should be made in a timely manner. Some people may have no signs, while others may exhibit some or all of these symptoms. A symptom of adrenocortical carcinoma may include a deepening of the voice or a swollen sex organs. Other signs of adrenocortical cancer include vaginal bleeding, an irregular menstrual cycle, and swelling of the breasts.
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The first sign of adrenocortical cancer is a deepening of the voice. The tumor may also cause swelling of the sex organs. While adrenocortical cancer usually doesn't have any symptoms, it can be detected with imaging studies. It can also cause bleeding of the breast and irregular menstrual cycles. Further, it may appear in the gastrointestinal tract.
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Adenomas are nonfunctioning adrenocortical cancers. They are benign and do not produce hormones. They may affect fluid and nutrient intake and sexual characteristics. Some of the most common symptoms of an adrenocortical cancer are thirst and sex-related reproductive issues. However, an adenoma does not produce any hormone.
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The most common symptom of adrenocortical cancer is an enlarged prostate. Adenomas are typically less than 4cm in diameter and can be treated without surgery. During their initial presentation, the disease does not usually have any signs. Some patients experience unspecific abdominal pain, vaginal bleeding, and increased blood pressure. They may also develop a deeper voice.
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The symptoms of an adrenocortical cancer are usually treated with surgery. A surgeon will remove the tumor. Surrounding tissue will need to be removed to make room for the new organ. Although the exact cause of adrenocortical cancer is unknown, it is believed to run in families. Genetic testing is recommended for individuals with a family history of the disease.
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Patients with these symptoms may experience unexplained pain or discomfort. These patients may feel full after a small meal. Any symptoms of hormonal imbalance should be examined by a medical professional, but a doctor may order additional tests to identify the cause. In rare cases, a recurrence of the disease will require treatment. The doctors will assess the patient's condition and decide on the next course of action.
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