There are many different types of astrocytomas in children. The type and location of the tumor will have an impact on the treatment. The child's age will also have an impact on the child's symptoms and general health. A doctor can recommend a treatment plan based on these factors. For example, a child who has a glioma in his or her cerebrum may receive different treatment than a child who is only three years old.
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Low-grade astrocytomas are common in children and adolescents. They tend to be benign and incurable. Surgical removal is the primary treatment, though it is not always possible. A surgeon may not be able to remove the entire tumour during surgery, which is why doctors often discuss other options. Surgical removal is the preferred treatment for astrocytomas in childhood, but it is not always the best option. Because the tumour is so high, it can damage normal brain tissue surrounding it, and the risk of spreading to the spine is minimal.
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Children with low-grade astrocytomas typically undergo surgery. While it is possible to perform total resection in such cases, the surgical procedure is limited in certain cases. Some pediatric astrocytomas are located in the optic chiasm and hypothalamus, and invasive surgery is not always possible. Some cases may also be associated with NF1, making total resection less feasible. If a child is diagnosed with a high-grade astrocytoma, it may not be amenable to surgery. A patient with WHO grade II astrocytoma may not respond well to surgery.
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Although low-grade astrocytomas have better survival rates than their lower-grade counterparts, survival rates depend on their location and the growth rate of the tumor. A surgical procedure must be performed with care to prevent harm to surrounding healthy brain tissue. Radiotherapy and chemotherapy may be necessary in high-grade astrocytomas. In cases where the cancer is large or asymptomatic, the treatment can involve radiation therapy and chemotherapy.
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While recurrent astrocytomas can occur anywhere in the central nervous system, it is rare in children and are generally treated in the same way as their first tumor. Typically, high-grade astrocytomas will recur within three years. However, the prognosis of this type of cancer depends on the location of the tumor. In some cases, astrocytoma treatment is limited only to the initial tumor and if it recurs.
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The primary treatment for astrocytomas in children is surgery. In some cases, a child's astrocytoma can be treated with surgery alone. Depending on the location and grade of the astrocytoma, surgical resection may be a poor option. Nevertheless, the surgeon should attempt to remove as much of the tumor as possible. Surgical resection is the best option for a child with a low-grade astrocytoma.
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A physical exam is an important part of a child's diagnosis of childhood astrocytomas. A doctor will check for general signs of health and any abnormalities, such as seizures. They will also examine a child's reflexes and conduct a neurological examination to check the functioning of the brain. Despite the possibility of an astrocytoma, the treatment for this type of tumor is usually centered on the location of the tumor.
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The majority of astrocytomas in children are low-grade. They are often similar to normal cells and grow slowly. In contrast, a small percentage of high-grade astrocytomas may spread rapidly. If the tumour is in the brain stem, surgery is likely to cause severe damage to the surrounding normal brain tissue. In addition, there are a few treatments for astrocytomas in childhood that are not appropriate for every child.
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A population-based study of astrocytomas in children eliminates the potential for referral bias. The authors of the study noted that a child with a hypothalamic-origin pilocytic astrocytoma was diagnosed with high CSF protein content, and the ventriculoperitoneal shunt could not cure the child. The child's parents maintained the external ventricular drain in the child, which was the only permanent treatment option available to this child.
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The main group of childhood astrocytomas is low-grade. They are indolent and generally have an indolent course. In fact, they represent 20 percent of all brain tumors and are considered WHO grade I tumors. The location of the astrocytoma is typically in the cerebrum, where it is frequently found in the optic nerve. MRI images of astrocytomas in children are usually characterized by a contrast medium-enhancing nodule within a cystic mass.
