Chordoma in Childhood Symptoms and Treatment - Oren Zarif - Chordoma in Childhood
When a child develops chordoma, a genetic change may be to blame. Children are born with a thin bar called the notochord running along their back. This notochord supports their spinal cord during their growth in the womb and eventually disappears after birth. This enables the spine to develop normally and chordomas begin when notochord cells divide too rapidly.
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During childhood, the most common presenting symptoms are diplopia, headache, and swallowing problems. In nearly half of the cases, the tumor is asymptomatic. In addition to headaches, other symptoms may include pyramidal syndrome and diplopia. Patients with these conditions should see a pediatric neurologist immediately to avoid further complications. While the cause of the chordomas is not fully understood, treatment options should be individualized.
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A PDQ cancer information summary is an independent review of the scientific literature. It provides information for clinicians, and does not constitute formal guidelines or recommendations. The PDQ cancer information summary for chordoma in childhood contains current information on diagnosis and treatment. It is not a policy statement of the National Cancer Institute. It should be used as a reference for patients. It does not provide recommendations or treatment.
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The symptoms and treatment of chordoma depend on the location of the tumor in the body. Intracranial chordomas block the flow of cerebrospinal fluid (CSF), and CSF can build up inside the skull. Hydrocephalus can have several symptoms, depending on age. The symptoms include headaches, double vision, and rapid eye movements. The cordoma in the cervical spine can also lead to neck pain, hoarseness, and earaches.
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Most children who have chordoma experience headaches, but their symptoms will vary. A PDQ is based on a review of the medical literature, and is not a policy statement. The PDQ does not present formal recommendations, but it offers current information about childhood chordoma. A PDQ will not replace a doctor's opinion. However, if your child experiences the above symptoms, the PDQ is a useful resource.
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When a child has chordoma, a doctor will perform a biopsy. A biopsy will help diagnose the disease. The doctors will check for high levels of brachyury, a protein that causes a tumor to grow. If your child develops chordoma in childhood, he or she may have other symptoms such as changed bowel or bladder habits, or a change in his or her bowel or bladder habits.
Because the disease affects such complex areas of the body, it requires specialized care.
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Because of its complex nature, treatment is unique to children. In some cases, surgery is necessary. A surgeon will remove a lump to evaluate the cause of chordoma. Often, a biopsy will show signs of chordoma in childhood. If it is suspected, the physician will recommend appropriate treatment. The underlying tumor may be causing pain, or the symptoms may be related to the disease.
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Despite its rare symptoms, chordoma in childhood may be a sign of a more serious medical condition. In addition to the symptoms described above, there are a number of additional symptoms that can make it difficult to diagnose. Fortunately, it is easy to find a doctor who specializes in pediatric chordoma and will help your child. If your child has a tumor in his or her skull, he or she may have an osteophyte, a tumor that is similar to a bone.
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A chordoma in childhood is a tumor in the neck that causes pain and is located in the skull. In children, a chordoma usually begins in the head but may occur anywhere on the body. The symptoms of the disease include a swelling on the ear or a lump in the chest. The doctor will then perform a biopsy to determine the exact cause of the tumor. These symptoms are often associated with an undiagnosed chordoma.
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Although chordoma in children is rare, it is a relatively common cancer among children and young adults. In adults, chordoma is more common in young people than in children, and is diagnosed in their early 50s or early 60s. The most common location of the tumor in children is the cervical spine. Females with this type of tumor are more likely to develop the disease than males. In childhood, the majority of chordomas are benign.
