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Chordoma in Childhood Symptoms and Treatments - Oren Zarif - Chordoma in Childhood

Mar 11, 2022
3 min read

Identifying the signs and symptoms of a chordoma in childhood can be tricky. A child with this condition may display neurologic deficits, pain, cranial nerve impairment, and even chondrosarcoma. It's also important to recognize any other symptoms associated with this tumor, such as bleeding or a fever. Thankfully, treatment for chordoma in children is now more effective than ever.

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While surgery and radiotherapy can cure a chordoma in childhood, it can also lead to other complications. The best treatments are often nonsurgical, such as chemotherapy. Proton beam radiation therapy can be an option. If the chordoma is located near the blood vessels or nerves in the brain, it cannot be removed with surgery. For these reasons, children with chordomas may need other treatment options.

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After surgical resection, high-dose radiotherapy is the standard treatment for children with chordoma. Although data on the effectiveness of this treatment in pediatric patients are limited, it has proven to improve overall survival. With the advent of proton beam radiation therapy, more precise doses of radiation can be delivered. A doctor may recommend radiation therapy as the final treatment for a childhood chordoma. This type of treatment is a more complex one, but it can be done successfully.

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In a case of an 11-year-old girl with persistent headaches, a physical examination revealed no abnormalities. A magnetic resonance imaging (MRI) study showed a two-cm sharply delineated mass on the caudal clivus. On T1-weighted images, it was homogeneously hyperintense, and it displayed strong heterogeneous contrast enhancement on the FLAIR sequence. Computed tomography confirmed that the tumor was soft-tissue with no bony tissue. This led to a chordoma diagnosis.

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The most common symptoms of chordoma in childhood are diplopia, headache, and swallowing problems. The median age at diagnosis was twelve years, with most patients experiencing diplopia, headache, and swallowing difficulties. All but three patients had locally recurrent tumors. Typically, the first treatment for a conventional chordoma in children is surgery. During surgery, the surgeon removes as much of the tumor as possible. If the tumor is not removed completely, the surgeon may administer radiation therapy to kill the remaining cells.

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A diagnosis of chordoma in childhood requires an examination and a diagnosis. A doctor will likely order a CT scan or MRI to rule out any tumors. During the first visit, he or she will likely be referred for a consultation. An MRI is necessary if the symptoms are causing a problem. The next step is a biopsy. Moreover, a biopsy is necessary to determine the extent of the disease and its treatment.

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Despite the rarity of chordomas in childhood, it's important to seek medical attention to determine the causes and symptoms of this condition. This rare type of bone tumor is connected to a disease called tuberous sclerosis, which causes benign tumors in the brain, eyes, and other parts of the body. However, unlike benign tumors, a chordoma may recur in other areas, such as the lungs or kidneys.

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Surgical treatments for chordoma are limited, but can be life-threatening. Surgical resection of the tumor is the first step in treatment and aims to reduce the volume of the tumor and to preserve the surrounding vascular and nervous tissues. Among pediatric patients, surgery is the most common choice for treatment. During the procedure, a surgeon will carefully dissect the affected area with a laser.

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In children, chordomas are often benign. If the patient's symptoms persist, they can be treated with surgery. In most cases, the child will be given an MRI. Some children may require radiation therapy or chemotherapy. Occasionally, a patient may require chemotherapy or radiation. The treatment for chordoma in childhood depends on the cause of the tumor. The onset of the condition should be early enough to avoid serious side effects.

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If the child's symptoms persist, a doctor should consult a specialist. In some cases, a pediatrician may recommend a different treatment plan. A cancer specialist can also refer the patient to a specialist. If the patient isn't aware of the symptoms of a chordoma, it's important to get a second opinion. If a doctor is unsure of the symptoms, they can call a geneticist.

 
 

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