Chronic Myelogenous Leukemia Symptoms - Oren Zarif - Chronic Myelogenous Leukemia
People with chronic myelogenous leukemia (CML) have a high number of white blood cells. These cells fight off infections and are a vital part of the immune system. Unfortunately, the white blood cells that are diseased are less resistant to infection than healthy ones, making them highly susceptible to infection. The symptoms of CML vary from person to person, and doctors will usually prescribe a course of treatment that will keep your white blood cell count at a safe level.
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Some of the most common symptoms of chronic myelogenous leukemia are listed below. The disease can also lead to spleen enlargement, causing a feeling of fullness. A large spleen can also cause pain in the left side of the body below the ribs. In severe cases, the disease can cause a high platelet count, which can lead to blood clots and stroke.
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A physical examination may reveal abnormalities, and a bone marrow biopsy will determine whether the disease is present. A doctor may recommend several tests to diagnose the disease. FISH analysis, which uses fluorescence to identify genetic material, is one test commonly used. A PCR test is another test that can make millions of copies of a segment of DNA. These assessments are useful for more in-depth evaluations.
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Some of the most common signs of chronic myelogenous leukemia include an increased white blood cell count. This causes the patient to develop frequent infections that last longer. Other symptoms include a decreased platelet count, which can cause easy bleeding and frequent nosebleeds. This condition can also affect the heart and may even cause joint pain. In severe cases, the patient may die from excessive bleeding or a stroke.
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Other symptoms of chronic myelogenous leukemia include an enlarged spleen. This can cause abdominal swelling and discomfort in the upper left portion of the abdomen. In the case of severe chronic myelogenous leukemia, a doctor may recommend a transplant or chemotherapy. However, patients with this condition should be evaluated for a diagnosis. It is important to remember that the symptoms of CML may not be immediately apparent.
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Among the symptoms of chronic myelogenous leukemia are fatigue, fever, night sweats, and weight loss. Many of these symptoms are often misinterpreted as those of other illnesses, and may be confused with other symptoms. The first and most important symptom is an enlarged spleen. If these symptoms are not properly identified, they may be due to anemia or other complications of the disease.
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A physical exam can identify any physical abnormalities. A bone marrow biopsy can be done to determine if there is cancer in the bone marrow. It is a type of blood cancer in which diseased white blood cells crowd out healthy red blood cells and produce anemia. As a result, a patient with chronic myelogenous leukemia can experience several symptoms.
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Besides fatigue and anemia, other chronic myelogenous leukemia symptom is a lowered platelet count. A low platelet count can prevent the healing process of minor trauma. An enlarged bone marrow can also lead to joint pain. In addition to these symptoms, the diseased platelets are stored in the bone marrow. In the latter phase, these cells cause the spleen to enlarge and even rupture.
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The disease has two distinct phases. The chronic stage is characterized by an elevated platelet count. In the first phase, the patient has a high platelet count. This condition will lead to an enlarged spleen and abdominal pain. The accelerated phase is characterized by a rapidly increasing platelet count. In this stage, patients with this disease may have a fever, thrombocytopenia, and a loss of appetite.
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In both chronic myeloid leukemia stages, the number of infected cells in the bone marrow is higher than that of healthy cells. The infected cells are characterized by a low-grade sensitivity to chemotherapy, which will suppress the growth of the cancer. Moreover, it will also be necessary to monitor the patient for a long time to ensure that the disease is not progressing to another stage.
