Myeloproliferative neoplasms, or CMLs, are diseases that affect the bone marrow. This soft, spongy part of the bone is the factory for making new blood cells from stem cells. People with CMLs have too many extra blood-forming cells, which can cause problems such as anemia, infection, and fatigue. In addition, they are susceptible to developing acute leukemia.
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The symptoms of chronic myeloproliferative neoplasms can be a combination of other conditions. For example, too many white blood cells can lead to acute leukemia, where the white blood cells become too abnormal and multiply rapidly. The disease is difficult to diagnose, but the symptoms can give you a clue as to whether you have the disease. Listed below are some of the most common symptoms of CML.
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An enlarged liver is one of the most common CML symptoms. An enlarged liver can cause abdominal discomfort. About two-thirds of patients with this disease have an enlargement of their liver. Other symptoms of Chronic Myeloproliferative Neoplastic Syndromes include joint pain, bleeding problems, and bone pain. These are not the only CML symptoms. In addition to these, other signs and complications of this disease can range from fatigue to anemia.
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Affected individuals may experience a variety of symptoms that vary according to the type of CML. Some people experience a feeling of fullness. An enlarged spleen can block blood vessels in the liver and lead to portal hypertension, which makes the liver enlarge and cause swelling in the abdomen. In addition, they may suffer from a reduced ability to perform activities of daily living.
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The most common CML symptoms are anemia and fatigue, although they can also be triggered by infection or a virus. As with any cancer, the condition can cause other complications as well. Fortunately, CML symptoms are easy to identify. During the early stages, patients may experience only a few symptoms, or they may have several. A physician should be able to distinguish between a few CML symptoms and a few of the most severe ones.
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The signs of a myeloproliferative disorder depend on the type of disease. They include an increased number of platelets and red blood cells, which can cause clots in the body. Additionally, people with CML may experience shortness of breath, weakness, and abdominal swelling. These signs are not indicative of a CML, but should be considered serious if you have CML.
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CML symptoms depend on the type of disease and its stage. The increased production of red and white blood cells may thicken the blood, resulting in blood clots. In addition, a patient with this disorder may experience a number of other symptoms, including an increased number of platelets and anemia. In some cases, the symptoms may be mild or asymptomatic. In some cases, chronic myeloproliferative neoplasms are accompanied by a sudden onset of fatigue.
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Some people may experience the following symptoms: anemia, and thrombocytopenia. The increased number of red and white blood cells can lead to anemia. The increased production of blood cells can also enlarge the liver, which can result in a swollen abdomen. This condition is also associated with inflammation and decreased bone marrow function. It is common for chronic myeloproliferative neoplasms to be related to genetic mutations of the Janus kinase 2 gene.
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A person with chronic myeloproliferative neoplasms may experience these symptoms as a result of an increased number of red blood cells. They may also experience increased blood pressure. These complications may lead to an enlarged liver or abdomen. Affected individuals should visit a doctor as soon as possible to get a diagnosis. A physician can treat the symptoms as quickly as possible.
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Some people may develop acute myelogenous leukemia after chronic myeloproliferative neoplasms. This type of MPN affects the bone marrow, which is the source of all blood. It is rare and typically occurs in older people and women. There is no cure for chronic myeloproliferative aplasia. However, it is important to seek out a physician as soon as possible.