Hairy Cell Leukemia Symptoms and Diagnosis - Oren Zarif - Hairy Cell Leukemia
The hairy cells of the blood that are characteristic of hairy cell leukemia are called "hairy cells." Treatment for hairy cell leukemia includes medical care. Patients who are refractory to chemotherapy may begin treatment with cladribine, a type of drug that has an 85 percent complete remission rate and a 10 percent partial response rate. This treatment is very effective and can help people with hairy cell lymphoma survive for up to 10 years.
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The diagnosis of hairy cell leukemia is confirmed with a physical exam and biopsy of the spleen. Several additional tests, such as BRAF mutations, may also be performed. One of the most commonly used lab tests for hairy cell leukemia is immunophenotyping, which identifies specific antigens on the cells. Other tests, such as bone marrow aspiration, can detect a "fried egg" appearance of the leukemic cells.
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A physical exam and biopsy of the spleen are two of the most common tests for hairy cell leukemia. A biopsy of the spleen will reveal the presence of hairy cells. This test is usually done as an outpatient procedure. After the results of the biopsy and spleen scan, patients must wait for several days for results. It is crucial to know the results of the tests to ensure the correct diagnosis and to plan treatment.
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A diagnosis of hairy cell leukemia requires several tests. These tests will determine whether the disease has responded to treatment. A complete response means that blood counts are normal and there are no abnormal cells in the blood, spleen, or bone marrow. Moreover, the number of abnormal cells in the bone marrow is reduced. The patient may experience fevers or chills. The doctor will also perform an evaluation of the lymph nodes and liver.
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The most important test is the complete blood count. Anemia and a low platelet count can indicate hairy cell leukemia. A full blood count can also be performed to rule out other causes of anemia. A peripheral blood smear will show a reduction or absence of monocytes. The presence of hairy rim cells is characteristic of this type of leukemia under a microscope.
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Other Hairy Cell Leukemia Symptoms include swollen lymph nodes, abnormal cells in the blood, and abnormalities in the spleen and bone marrow. It may also affect the spleen and the liver, and cause abdominal and neck pain. If a blood test shows that the hairy cells have invaded these organs, the doctor will most likely recommend that further tests be performed.
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Other Hairy Cell Leukemia Symptoms include severe bleeding. The most common symptom is anemia. In addition, patients may experience nosebleeds, increased bruising, and abdominal pain. Infections are common in patients with hairy cell leukemia. The patient may also experience pain in the spleen, and may feel full before eating. These symptoms can be indicative of a serious underlying condition.
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Several tests are performed to diagnose hairy cell leukemia. A full blood count will show anemia and a low white blood cell count. A full blood smear will show the number of hairy cells and the presence or absence of monocytes. Occasionally, patients with hairy cell leukemia may experience early fullness during meals. Further tests will help to confirm the diagnosis. When there are hairy cells in the blood, the patient will experience anemia and bone marrow pain.
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Hairy cell leukemia can affect the liver. The disease affects the liver and the spleen, which can result in an accumulation of fluid in the abdomen. It can also affect the brain and lymph nodes. A blood smear will show a reduction or absence of monocytes in the patient's blood. Additionally, the doctor will check for hairy cells in the bone marrow.
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A bone marrow biopsy and a sample of the patient's blood are necessary to determine the type of hairy cell leukemia. In the early stages, a diagnosis can be made based on a spleen biopsy and a blood sample taken from the patient's marrow. In some cases, hairy cell leukemia can be cured by chemotherapy. In some cases, it may respond to treatment, but it cannot cure the disease.
