Myelodysplastic syndromes are a group of diseases in which blood cells in the bone marrow fail to produce enough red blood cells. As a result, the body becomes weak and prone to infection. Some people with the condition suffer from recurrent infections and low white blood cell counts. People with these conditions should avoid contact with people who are sick, and should get tested for the disease. There are several risks associated with myelodysplastic syndromes, including heavy metal exposure.
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The World Health Organization has divided the different myelodysplastic syndromes into different subtypes, based on the type of blood cells involved. In single-lineage dysplasia, people have a very low number of mature blood cells. In ring sideroblasts, the existing red blood cells in the bone marrow contain excessive iron rings. This can lead to anemia.
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Myelodysplastic syndromes can cause anemia and anaemia. Both types affect the red blood cells. In refractory anemia with ring sideroblasts (RAEB), immature red blood cells develop iron deposits around their nuclei. Because of this, patients with RAEB-2 are at a higher risk of developing acute myeloid leukemia.
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People with myelodysplastic syndromes can develop the disease at any age. This disorder is more common in older adults. It affects approximately twenty to forty per 100,000 people. In the U.S., there are 20,000 new cases diagnosed annually. The prevalence of MDS is rising with the growing proportion of the elderly population. In the United States, the exact number of new cases is difficult to determine because of the lack of reporting of mild cytopenias.
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Symptoms can vary from person to person depending on the type of blood cells that have been affected. During the course of an MDS, symptoms may include fatigue, weakness, bruising, or anemia. In addition, some people may suffer from a combination of the symptoms or both. Depending on the type of blood cells, treatment will depend on the specific causes of these symptoms. While myelodysplastic syndromes are rare, the disease can be life-threatening.
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Patients with MDS may experience a wide range of symptoms. Treatments depend on the severity and type of the disease. Some people with myelodysplastic syndromes may experience depression, anger, or other unpleasant emotions. Their symptoms may also be caused by underlying health issues. Symptoms of myelodysplastic syndromes can be difficult to deal with, but with proper care, people can live a healthy, normal life.
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Myelodysplastic syndromes are a group of cancers that prevent the body's bone marrow from producing healthy blood cells. As a result, the body is left with many immature and defective blood cells that die in the bloodstream. The result is low levels of healthy blood cells and increased bleeding. Affected people may suffer from anemia, excess bleeding, and infections.
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MDS-U is a less common type of MDS. In patients with this condition, the bone marrow does not produce enough red blood cells and is therefore anemic. Because patients with this condition usually do not develop leukemia, their prognosis is good. MDS-U is associated with an abnormal chromosome in the bone marrow. MDS-U is the least common type of myelodysplastic syndromes.
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MDS-EB is subdivided into two types, MDS-EB1 and MDS-EB2. MDS-EB-2 has more blast cells in the blood and bone marrow. Previously, this type was known as "refractory anaemia with excess blasts." In addition, the platelet count is normal. In addition to the two types of MDS-EB, FAB is used to categorize all MDS.
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MDS is more common in older people, but can occur at any age. The cause is unknown, but some research has indicated that aging is associated with an accumulation of mutations in bone marrow stem cells. There is no cure for MDS, and it can progress to acute myeloid leukemia (AML).
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People with Crohn's disease should seek medical advice from a qualified healthcare provider. They can also get referrals through advocacy groups, clinical trials, or articles published in medical journals. Specialists in this field may be harder to find, but they are available. You can use the Internet to search for a specialist in your area. If you're unsure about the symptoms of the disease, you can look for them online.
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Because some people with MDS will progress to AML, you should seek treatment as soon as possible. Depending on the type of disease you have, treatment will vary. Treatment options will depend on the risk of transformation and the number of normal blood cells. A doctor will prescribe a treatment based on your risk of converting to AML. You can be treated for your condition if you have a good prognosis.