Neuroblastoma Symptoms - Oren Zarif - Neuroblastoma
- Oren Zarif
- Apr 11, 2022
- 3 min read
The symptoms of neuroblastoma can vary greatly, depending on the size and location of the tumor. If it is located in the spinal cord, patients may experience pain in the neck or abdomen, and swelling in the face. Bone pain may be associated with the disease if the tumor has spread to the bones. Some children may experience pain in the legs or arms and/or weakness due to bone involvement. Other symptoms may include pain in the bones, numbness in the extremities, and decreased red or platelet counts. Occasionally, diarrhea and high blood pressure may occur.
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When the tumour has spread to distant parts of the body, it is called stage 4S. Stage 4S neuroblastoma has a better outlook than stage 3 and 4. At this stage, the cancer has spread to the liver, skin, or bone marrow. The cancer cells have not yet spread to nearby lymph nodes. Surgical removal may be needed in some cases. In addition, the cancer may have spread to the skin and bones, which can cause the child to develop a fever or other symptoms.
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Although neuroblastoma is rare in children, it is possible to pass the cancer on to future siblings. However, if the child does develop the tumor in the brain, doctors should be able to confirm the diagnosis by ordering blood tests and urine chemistry tests. Urine catecholamine excretion may be elevated because of the tumor. Multiple imaging studies are often done in children with neuroblastoma to determine the primary tumor and the presence of metastases.
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Treatment options for neuroblastoma will depend on the specific type of tumor and whether or not it has spread to lymph nodes near the area of the brain. However, treatment may not remove the entire tumor, since the tumor has spread to the surrounding lymph nodes. Further, the cancer may have metastasized to other parts of the body, including the bone marrow and skin. Therefore, it is vital to consult with a medical professional as early as possible.
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The first signs of neuroblastoma include a large lump in the abdomen. Children with neuroblastoma may also complain of feeling full. In addition, they may also experience abdominal pain and constipation. The lump is not painful, but it is not normal for them to sweat. If the tumor has spread, however, the symptoms of neuroblastoma may be different. In addition to symptoms like pain and swelling, neuroblastoma also has some additional characteristics.
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Patients with neuroblastoma may undergo chemotherapy, radiation therapy, or both. During treatment, doctors may also administer immunotherapy, which trains the body's immune system to attack the cancer cells. During immunotherapy, antibodies are injected into the body, which attacks abnormal cells in the body. These antibodies attach to the GD2 proteins in neuroblastoma cells, signalling the immune system to attack the cancer.
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A doctor may order blood tests, CT scans, MRIs, and urine tests. A bone scan may be necessary to confirm a diagnosis of neuroblastoma. Bone marrow biopsy may also be performed. Bone marrow is the sponge-like tissue that forms the blood in the center of large bones. The doctor will use a biopsy of this bone to determine whether neuroblastoma has spread to the bone.
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Because the tumors in neuroblastoma are often arising from immature nerve cells, the symptoms of this cancer can be difficult to detect. However, parents should discuss the symptoms of neuroblastoma with their pediatrician to determine the best course of treatment. The diagnosis of neuroblastoma is often made possible by the presence of other tumors elsewhere in the body. This includes the bones, spinal cord, and the lymph nodes.
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Surgery is often used in the treatment of neuroblastoma. Surgical removal of the tumor is an option. The doctor may remove the tumor to remove it safely. Some children may receive chemotherapy before surgery. The outcome of the surgery may also depend on the severity of the disease and the child's risk category. If the cancer is still present after chemotherapy, the child may need radiation therapy. If these options do not work, the parent should consider clinical trials.
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The symptoms of neuroblastoma depend on where the tumor is located, how far it has spread, and how much hormones are produced. The symptoms of neuroblastoma may be confused with other health conditions, so parents should consult a pediatrician as soon as possible. A doctor will be able to determine the cause of the symptoms and provide treatment. There are many resources available to help parents of children with neuroblastoma.