Having Pancreatic Neuroendocrine Tumor (PNET) symptoms can be a difficult process. A pancreatic neuroendocrine tumor may not be apparent until it has spread to nearby organs or blood vessels. It may start in the pancreas and have only limited spread, or it could have already spread to the large intestine, spleen, or bile duct. If the cancer has spread to these organs, it will be called metastatic cancer.
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Among the most common symptoms of pancreatic neuroendocrine tumors are indigestion, diarrhea, bloating, weight loss, and abdominal pain. Other symptoms may include low blood sugar and muscle weakness. People with pancreatic cancer often experience low blood potassium levels. These symptoms can lead to a range of other complications, such as heart disease. Some symptoms are common and others may be subtle.
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There are two types of pancreatic neuroendocrine tumors: nonfunctional (PNET) and functional (PNET). Functional tumors make hormones, and cause symptoms based on the type of hormones they produce. Insulinomas are the most common types of functional PNETs, while nonfunctional tumors produce no hormones. Nonfunctioning tumors are larger and more likely to be cancer than nonfunctional ones. Although PNET is rare, it can cause symptoms and is often a dangerous medical condition. It is best to consult with a physician for a diagnosis and to learn more about the symptoms.
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In addition to these specific symptoms, patients with these tumours should be aware of the possibility of developing a gastrinoma (GNET). These tumours produce gastrin, which increases the amount of glucose in the blood. This excess can lead to ulcers, which can be life-threatening. Symptoms of this condition may include anemia, facial flushing, or diabetes. The most common treatment for pancreatic NET is surgical removal.
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Treatment for pancreatic neuroendocrine tumors is largely determined by whether the tumor is locally or metastatic. Local treatments, such as surgery, remove cancer cells from a single area. Systemic treatments, on the other hand, aim to kill the cancer cells from multiple locations in the body. For metastatic pancreatic neuroendocrine tumors, the treatment options include chemotherapy or targeted therapy.
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Active treatment is necessary when the tumor begins to spread. If the tumor is still small, it can be removed surgically or with drugs. Active surveillance is another option for patients who do not wish to undergo surgery. Surgical removal of the tail or body of the pancreas may also be an option. The duration of treatment depends on the symptoms and the tumor's progression. Symptoms and treatments vary, so it is important to be aware of them.
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Although there is no specific test to detect pancreatic neuroendocrine tumors, it is important to see a doctor to receive a biopsy. Diagnostic tests for these tumors can determine the extent of the disease. Some patients may not have symptoms, or the tumor may be so small that it is not visible. Fortunately, advanced-stage patients may present with symptoms of tumor bulk and require surgical resection or hepatic-directed therapies to remove the tumor. Treatment options for advanced-stage PNETs may include a combination of surgery and chemotherapy regimens.
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Most people who have Pancreatic Neuroendocrine Tumor (PNET) do not experience any symptoms associated with hormone hypersecretion. This type of tumor usually occurs incidentally during imaging tests for another reason or at a later stage, when the patients have become symptomatic from the tumor bulk. Symptoms of pancreatic NET can be quite puzzling and diverse, and the treatments for these patients are based on the hormones secreted by the tumor.
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Some of the common symptoms of Pancreatic Neuroendocrine Tumor include:
In addition to symptoms, people who have Pancreatic Neuroendocrine Tumor can experience other complications as well, including cardiac failure, bone fracture, or even death. Early detection is critical to improving prognosis. Neuroendocrine tumors are rare, accounting for less than one percent of all malignant disorders in the United States. They usually arise in the intestine, lungs, or appendix.
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The symptoms of Pancreatic Neuroendocrine Tumor are difficult to detect because they can be caused by other health conditions. A healthcare provider can diagnose a Pancreatic Neuroendocrine Tumor by looking at your health history, conducting a physical exam, and conducting blood tests to detect the presence of the tumor. Once the diagnosis is made, the treatment can begin. A biopsy is required in some cases.
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Recurrent Pancreatic Neuroendocrine Tumor Patients may experience many emotions and worry about the return of their pancreatic neuroendocrine tumor. While remission is an option, the fear of tumor growth is constant. Understanding the risks of recurrence will help you prepare for it. Recurrent Pancreatic NET is also known as distant recurrence. It may recur in the same place or near it.