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Pancreatic Neuroendocrine Tumors Symptoms - Oren Zarif - Pancreatic Neuroendocrine Tumors


A pancreatic neuroendocrine tumor (pNEN) develops when the cells in the pancreas that produce hormones undergo mutations. These mutations in DNA, the material responsible for instructing the body's chemical processes, cause the cells to grow out of control, forming tumors. Moreover, these tumors can break free and spread to other organs. Men are more susceptible to developing this cancer than women.

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Although pancreatic neuroendocrine tumors are rare, they can cause many adverse effects. They develop in the islet cells, which make insulin, and secrete hormones such as adrenocorticotropic hormone (ACTH). Treatment for pancreatic NETs may involve surgery. However, surgery is an option that may reduce some of the side effects of treatment.

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During treatment, the symptoms of pancreatic neuroendocrine tumors may include pain, nausea, vomiting, abdominal swelling, or a rash. However, some of these symptoms are caused by other conditions. To identify the underlying cause of your symptoms, talk to your healthcare provider. During a physical exam, they will examine you and check your symptoms. Blood tests will reveal the presence of high hormone levels in your blood.

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Symptoms of pancreatic neuroendocrine tumors may include blood in the stool or black tarry stools. Similarly, your skin might become yellow and irritated. You may also experience diarrhea that becomes more watery and frequent. You might also experience flushing, a sensation of warmth, or even weakness in your muscles and legs. Your doctor may perform imaging tests to determine whether the tumour has spread throughout your body.

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A multidisciplinary approach is required for the treatment of pancreatic neuroendocrine tumors. Medical management includes surgery and chemotherapy, which is used to minimize recurrence rates and control symptoms of metastatic pancreatic cancer. The multidisciplinary approach to pancreatic neuroendocrine tumors is led by physicians who specialize in diagnosing and treating this condition. These professionals work together to ensure a smooth, comfortable experience for patients and their families.

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The most common symptoms of pancreatic neuroendocrine tumors are low blood sugar and enlarged liver. These symptoms can result in a range of problems, including loss of appetite and weakness. If the tumor spreads to other parts of the body, it can lead to blood clots, such as in the legs or lungs. If not detected early enough, they can even cause coma and death.

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pNET is less common than pancreatic cancer and has a better prognosis than its counterpart. Earlier, it was called pancreatic islet cell tumors, and is believed that about 10 percent of cases are hereditary. However, pancreatic NET symptoms vary greatly from patient to patient. However, treatment options may depend on where the tumor is located, how far it has spread and if the patient has MEN1 syndrome.

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Nonfunctioning pNENs also produce symptoms, although these symptoms are less severe. Most of the time, these pNENs manifest as abdominal pain and sometimes an associated abdominal mass. In severe cases, symptoms may include nausea, indigestion, diarrhea, and yellow skin. If the tumor is not detected early enough, it may spread to other organs, including the brain or the lungs.

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Although symptoms of pancreatic neuroendocrine tumors differ from one another, they are usually similar and may be confused with other conditions. Some of these symptoms are similar to those of irritable bowel syndrome, a nonfunctioning tumor. For example, a pancreatic neuroendocrine tumor may be mistaken for an irritable bowel syndrome, with abdominal discomfort that can be relieved by using the bathroom.

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Most pancreatic NETs don't cause symptoms until they reach the advanced stage, although they may also produce the same hormones as more common types of pancreatic cancer. The symptoms of pancreatic NETs vary greatly, and they may occur at any stage of the disease. For instance, people with gastrinoma may experience stomach ulcers, weight loss, or abdominal pain.

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VIPomas, which produce vasoactive intestinal peptide, are another type of pancreatic NET. They cause watery diarrhea and dehydration. Patients with this type of tumor often require intravenous fluids and somatostatin analogs. The latter are effective treatments for diarrhea associated with VIP syndrome. However, they are extremely rare and may not be diagnosed in all patients.

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While there is no cure for this disease, there is hope for people with the disease. Treatment for the disease depends on the stage of the tumor and its location. With early diagnosis and removal of the tumor, a 5-year survival rate is possible. Treatment is based on a patient's stage and whether or not the tumor has metastasized to other areas of the body. Surgical treatment can remove the tumor.

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