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Pancreatic Neuroendocrine Tumors Symptoms - Oren Zarif - Pancreatic Neuroendocrine Tumors


Some people may experience a variety of different symptoms from a Pancreatic Neuroendocrine Tumor (pNET). Some patients have diarrhea that starts as black, tarry stool and improves over time. Others may experience flushing, nausea, weakness, and muscle cramps. The most common symptom of pNET is diarrhea, though other symptoms may include vomiting or muscle cramps. In addition to diarrhea, these people often experience problems digesting food.

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One of the symptoms of pancreatic neuroendocrine tumors is the loss of potassium. This can be a dramatic change when the body experiences a bout of diarrhea. The kidneys also produce a hormone called glucagon, which causes weight loss and diarrhea. Patients who experience any of these symptoms should seek immediate medical attention. Pancreatic neuroendocrine tumors can also spread to other areas of the body.

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Because of the similarity between pancreatic cancer and a neuroendocrine tumor, many people often confuse one type of pancreatic cancer with another. In the case of a pancreatic neuroendocrine tumor, however, the symptoms may be unrelated to another ailment. While a pancreatic tumor starts in the pancreatic exocrine cells, the majority of the body is made of exocrine cells. The exocrine cells are responsible for making digestive enzymes, while a pancreatic neuroendocrine tumor starts in the endocrine cells.

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Symptoms of a pancreatic neuroendocrine tumor can include low blood sugar, abdominal pain, and weight loss. Some people may have diabetes, or both. Other people may experience low blood sugar, which can lead to constipation or weakness. Some patients will experience a yellowing of the skin or eyes. Another symptom may be fatigue. There may be no visible symptoms at all.

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In rare cases, a tumor may not be found in the pancreas, but symptoms of a tumor can occur. The tumor may be non-functioning or functioning. Nonfunctioning NETs produce no hormones and can grow large before being diagnosed. In addition, they may cause pain in the abdomen, lack of appetite, and weight loss. Carcinoid NETs are more common in other parts of the digestive system and can develop in the pancreas.

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A pancreatic neuroendocrine tumor may produce too much hormone. If it is not cancerous, it will produce too little or too much of the hormones that regulate body sugar and metabolism. When this happens, the symptoms of pancreatic neuroendocrine tumors will vary. A few people may experience stomach pain or gastric ulcers, which can be life-threatening. Fortunately, some symptoms can be prevented.

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A family history of pancreatic neuroendocrine tumors increases your risk. People with MEN1 syndrome have a greater chance of developing a pNET. If your family history has pancreatic neuroendocrine tumors, you should consider genetic testing to determine if there are any inherited diseases. If you are unsure of your risk for pNET, your healthcare provider will recommend screening for pNET, even if symptoms do not appear.

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Treatment options for a pancreatic neuroendocrine tumor include surgery. Surgery, including a laparotomy, can remove the tumor. However, the chances of recovery are lower when the cancer cells have spread. Despite the low chances of cure, medications can help relieve the symptoms of excess hormones. Patients with pancreatic cancer may benefit from medications to relieve the symptoms associated with excess hormone production.

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Despite the fact that the incidence of pancreatic NET has increased due to improved diagnosis and classification, it is still rare and the disease is difficult to detect. Its diverse clinical syndromes make it difficult to diagnose it in the early stages. As such, it is important for medical oncologists to be knowledgeable about the symptoms of pancreatic NET. When these symptoms are present, however, they may be warning signs of a more serious condition.

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