Primary Central Nervous System Lymphoma Symptoms- Oren Zarif - Primary Central Nervous System
- Oren Zarif
- Apr 8, 2022
- 3 min read
The following article will discuss symptoms of Primary Central Nervous System Lymphoma. These symptoms may be similar to those associated with other types of lymphomas. However, they may also be unique to this condition. Listed below are some of the most common symptoms of this condition. If any of these symptoms apply to you, make an appointment with a healthcare provider to have a thorough diagnosis. In addition, you should note that CNS lymphoma has very aggressive symptoms, so you should see a doctor as soon as possible.
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MRI of the brain is the first test recommended in the diagnosis of suspected primary central nervous system lymphoma. Lesions are often located in the periventricular region and are hypo or hypermetabolic on T1. On CT, the lesions are generally hyperattenuating with a ring-like enhancement. In 80% of cases, there are no calcifications. Primary CNS lymphoma symptoms include enlarged tumor size, headache, and confusion.
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The symptoms of primary CNS lymphoma are similar to those of secondary CNS lymphoma, although they are more severe. The disease is generally diagnosed in people with suppressed immune systems, such as those who have HIV/AIDS or are older. It is important to note that primary CNS lymphoma has a different prognosis and treatment than non-Hodgkin lymphoma. However, the incidence of primary CNS lymphoma has increased significantly since the end of the century.
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Currently, chemotherapy is the first treatment for CNS lymphoma. Treatment is most effective when the tumor has not spread beyond the cerebrum, which is the largest part of the brain. Patients with CNS lymphoma must be under 60 years of age and still have a stable immune system to undergo the treatment. Moreover, patients must be free of any other diseases that can affect their ability to carry out daily tasks.
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Diagnosing this condition requires frequent visits to a medical professional. A physical exam and neurological examination can detect this condition. Brain scans may also be done to check for any signs of the disease. MRI scans are a common way to diagnose primary central nervous system lymphoma. The scans may also detect cancer cells in the brain or spinal cord. Once diagnosed, treatment will be determined.
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HIV infection and AIDS are both risk factors for CNS lymphoma. HIV infection can weaken the immune system and increase the risk of developing this condition. Tests for HIV antibodies can take up to six months to become positive. Therefore, you must undergo testing as soon as you notice symptoms of CNS lymphoma. Once you've had a biopsy, your doctor will recommend treatment.
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In addition to standard treatments, patients may also opt for clinical trials, which test out new cancer treatments. Although clinical trials are not suitable for everyone, they can help patients manage their symptoms. Patients are encouraged to contact the medical team to receive additional support in the meantime. For more information, download our fact sheet on Primary Central Nervous System Lymphoma Symptoms. The disease is rare and can be treated with early diagnosis and treatment.
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Patients diagnosed with PCNSL are typically in their seventh decade of life. The majority of patients present with progressive myelopathy, and about 64 percent exhibit constitutional symptoms. Other common symptoms include back pain and lower motor neuron signs such as areflexia or flaccid paralysis. And there is no definitive cause for these symptoms. However, patients with PCNSL should seek the proper diagnosis and treatment, as it may be a result of a different underlying condition.
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Although primary CNS lymphoma is rare, it can present with a number of symptoms and complications. It is a type of NHL in which malignant lymphocytes develop in the spinal cord and brain. These tumors put pressure on the structures of the brain and spinal cord, and may even cause significant neurological symptoms. It is unknown what causes primary CNS lymphoma, but it is thought to start in the body's lymphatic system. People with weakened immune systems and certain infectious diseases are at a greater risk.