Primary Peritoneal Cancer Symptoms - Oren Zarif - Primary Peritoneal Cancer
- Oren Zarif
- Apr 9, 2022
- 3 min read
A type of cancer called primary peritoneal cancer starts in the lining of the abdominal cavity, the peritoneum. The peritoneum clings to the internal organs and also produces a lubricant to make organ movement easier. Because it is a rare type of cancer, it is also important to distinguish it from secondary peritoneal cancer, which can develop anywhere in the body.
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Treatment for this type of cancer will depend on whether the cancer is confined to the abdominal cavity or spread to other organs. Surgical treatment involves the removal of the affected abdominal tissue by a surgeon. Cytoreductive surgery, which removes more cancerous tissue, has improved the outlook for peritoneal cancer patients. If primary peritoneal cancer has spread, patients may also undergo chemotherapy to shrink the tumor and kill remaining cancer cells. Today's newer chemotherapy drugs can enhance the effectiveness of this treatment.
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Screening tests are also important to diagnose this cancer. Patients can be identified with a genetic test known as OVA1, which is a combination of five biomarkers. Imaging studies may also be helpful in assessing symptoms of peritoneal cancer. Often, an ultrasound will be used, but an MRI scan of the abdomen and pelvis may be beneficial as well. Upper GI series may also be ordered. However, most people will wait for their symptoms to develop before undergoing treatment. This may delay side effects of treatment.
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While the symptoms of peritoneal cancer may be difficult to pinpoint, the earlier a diagnosis is made, the better. The five-year survival rates of ovarian and fallopian tube cancer are about sixty percent and thirty-nine percent, respectively. However, survival statistics for primary peritoneal cancer are much lower because of the lack of large studies. A 2012 study of 29 patients diagnosed with primary peritoneal cancer reported that the average survival time was 48 months.
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Women with peritoneal cancer often experience gastrointestinal symptoms that can be different from those seen in women with gynecologic cancer. The cancer is often difficult to detect, and in some cases, doctors don't even recognise it. However, if a woman has symptoms of primary peritoneal cancer, the symptoms of this cancer are usually more easily mistaken for another medical condition, such as tuberculosis or ovarian cancer.
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Although the clinical diagnosis of primary peritoneal cancer is not always straightforward, imaging findings are a critical component of the evaluation process. It is important to understand how imaging techniques will help distinguish the various types of primary peritoneal cancer, including the overlapping forms of ovarian and lymphomatous peritoneum. The most important factor in determining whether or not you have a cancer is primary peritoneal sarcoma is to determine the location and size of the tumor.
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Primary peritoneal cancer is a type of disease characterized by cellophane-like tissue that covers the abdominal organs. This protective layer prevents the organs from sticking together. Peritoneal lining cells originate from the same cell type that makes up the ovary. When they transform into cancerous cells, the peritoneum becomes the site for the spread of primary peritoneal cancer. The peritoneum is located anywhere inside the abdominal cavity, including the omentum, which hangs from the abdomen and wraps around the intestines.
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The most common imaging features of primary peritoneal serous carcinoma are peritoneal nodules and omental masses. Both of these areas are critical sites for lymphatic clearance and may be accompanied by peritoneal masses or calcifications. Psammoma bodies may be present in 30% of cases. On CT scan, intratumoral necrosis is also evident. Lastly, malignant ascites is a hallmark of desmoplastic small round cell tumors.
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A biopsy may reveal tumors in the ovaries and fallopian tubes. This may indicate primary peritoneal cancer, but sometimes a laparotomy is necessary to diagnose the disease. The cancer will then be staged according to its size and extent. This will help your doctor determine the most effective treatment. Primary peritoneal cancer and ovarian cancer are similar in their staging system and treatment, but they are treated differently.
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Surgical treatment for peritoneal cancer involves removal of the uterus, fallopian tubes, ovaries, or a portion of the omentum. Surgery for this type of cancer is typically referred to as cytoreduction surgery or debulking surgery. The goal of the surgery is to remove the most cancer while preserving as much of the peritoneum as possible. If the cancer has spread to other parts of the abdomen, surgery may not be effective.