Whether you have been diagnosed with pancreatic cancer, or you're curious about the symptoms of pancreatic neuroendocrine tumors, it's important to seek treatment as early as possible. Symptoms of pancreatic cancer may vary, from mild to severe, and they're based on the individual. Listed below are some common symptoms of pancreatic neuroendocrine tumors.
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Non-functional neuroendocrine tumors form in the endocrine cells of the pancreas, but do not produce hormones. Because they do not produce hormones, they are often discovered incidentally on imaging studies, which are typically ordered to diagnose another medical condition. However, large tumors can cause pain and discomfort in the upper abdominal region, as they compress surrounding structures. Surgery is the primary treatment for pancreatic neuroendocrine tumors.
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Other symptoms of pancreatic neuroendocrine tumors may include blood in the stool or black, tarry stools. Some patients also develop jaundice, a yellowing of the skin. Diarrhea may become more frequent or watery and face may feel warm. Imaging tests may be necessary to determine whether the pNET has spread to other parts of the body.
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While the cause of pancreatic neuroendocrine tumors is unknown, the symptoms of these cancers are consistent with those of other types. The presence of these symptoms could indicate a more advanced stage of pancreatic cancer or another health condition. Pancreatic neuroendocrine tumors are very common in both men and women, but men are more likely to develop them than women. For this reason, it's important to seek medical attention early.
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The most common type of pancreatic neuroendocrine tumors is insulinomas. This type produces insulin, which regulates blood sugar levels by transporting glucose into cells, fat cells, and the liver. In addition to these symptoms, insulinomas can cause low blood sugar, muscle weakness, and anemia. Patients may experience nausea and muscle weakness. Although symptoms of pancreatic neuroendocrine tumors vary, they are a warning sign that it is time for diagnosis.
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A nonfunctioning pNEN may not produce symptoms, but can cause other complications. It may cause abdominal pain and a mass, as well as nausea and indigestion. It can also cause yellow skin and blood in the gastrointestinal tract. Nonfunctioning pNENs may bleed into other areas of the body. They can lead to a fatal illness, and the symptoms are not always immediately obvious.
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In addition to the symptoms of pancreatic cancer, you may have some other affliction. Pancreatic neuroendocrine tumors often mimic symptoms of other diseases. Because the pancreas is comprised of exocrine cells that secrete digestive enzymes, it may be difficult to distinguish them from other illnesses. They may cause fatigue, blurred vision, and fast heartbeat.
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Functional pancreatic NETs produce hormones, which cause specific symptoms. The most common types of pancreatic neuroendocrine tumors are insulinomas, gastrinomas, and gastrinomas. Insulinomas can cause low blood sugar, and gastrinomas produce gastrin, which can lead to stomach ulcers and severe acid reflux. Nonfunctioning pancreatic NETs rarely cause symptoms, and are typically large and inoperable. Although rare, pancreatic neuroendocrine tumors are the result of an abnormality of the exocrine cells.
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Although rare, gastroenteropancreatic neuroendocrine tumors may lead to pain or skeletal-related events, which can affect a patient's quality of life. In addition to the symptoms of pancreatic cancer, gastroenteropancreatic neuroendocrine tumors are associated with significant morbidity and mortality. Early detection and treatment may improve survival rates for patients.
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While the incidence of pancreatic neuroendocrine tumors is extremely rare, the diagnosed incidence has increased dramatically due to improved detection and classification. Diagnosis is often difficult due to the variety of symptoms. A multidisciplinary approach to diagnosis and treatment is recommended, with surgical and nonsurgical treatments for localized tumors.
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During the initial stages of the disease, radiation therapy may be used to control symptoms.
A biopsy is another option for pancreatic neuroendocrine tumors. A biopsy of the cancer may be necessary to find the exact location and extent of the disease. Surgery may also be necessary to remove the tumor. Treatment options depend on the type of pancreatic NET and the presence of MEN1 syndrome. Patients may experience any combination of the symptoms, and their doctor may recommend a treatment.
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If you've been experiencing symptoms of pancreatic neuroendocrine tumors, the best course of treatment will be surgical removal. However, you need to know that the surgery may be painful and requires a surgical procedure. It is important to remember that the symptoms of pancreatic neuroendocrine tumors are often similar to those of other conditions. You may even have these symptoms when you're being tested for other conditions.
